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The use of heated tobacco can also expose users to harmful chemicals that are present in the tobacco leaf, even if the tobacco is not burned

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These guys were all heavy smokers with dozen of abortive attempts at quitting between them, and yet here they were smoke freeand happy about itfor weeks

So, it's hard to separate the effects of cannabinoid compounds on the cardiovascular system from the hazards posed by the irritants and carcinogens contained in the smoke