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Tobacco-based wraps introduce nicotine, tobacco-specific nitrosamines, and additional combustion compounds not present in rolling paper

Cannabis and vasoconstriction Cannabis has long been thought to cause vasoconstriction, in which the walls of a blood vessel (particularly the arteries and arterioles) contract, narrowing the channel and restricting blood flow along it

Of course, the concentrations and contents in e-liquids and vapors may have different effects once heated, atomized, and metabolized in vivo settings, so we should be cautious to interpret these studies