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A recent review of therapeutic drug monitoring data demonstrated a reduction in concentration/dose of amitriptyline, escitalopram and mirtazapine in smokers, even when age and sex variables were accounted for [25]

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Similarly, while the MAPKAP1 site (MK) does show appreciable cleavage in the eGFP and CAT fusions, the level of cleavage is quite low compared to the nearly 100% seen with MAPKAP1 itself in Figure 1A