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Surgeon General Vivek Murthy released an advisory highlighting alcohol use as the third leading preventable cause of cancer, after tobacco use and obesity

60,62 Mahmoud et al 54 described 0.34 kg/m 2 lower BMI in recipients receiving GLP-1RAs, versus 0.015 kg/m 2 gain in controls

Members who discontinued their medication prior to 12 months still experienced more average weight loss than real world evidence at the 12-month mark (13.1% vs 6.8%)

In the current study which did not undergo peer review the researchers assessed the likelihood of a dementia diagnosis within 5 years of starting a GLP-1 receptor agonist or another diabetes medication using a cohort of 549,822 patients aged 60 years or older with type 2 diabetes

PMID: 40280135 Oncogene TMSB4Y restrains sphingomyelin synthesis via de novo purine synthesis to exert a tumor suppressor function in male esophageal squamous cell carcinoma