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11 As a consequence, women who use these agents on a long-term basis may lose the beneficial effects of dopamine, which has a direct impact on the endocrine system, autonomic regulation, motivation, desire, and reward

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Therefore, the ACSL4-PUFA pathway is likely not involved in lipid peroxidation in ER+ cells lines, whereas it is in TNBC cell lines with higher ACSL4 levels