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Isoenzyme GST P1-1 is notably induced in lung, colon, and stomach cancers and was found to be implicated in cellular resistance to chemotherapeutic agents ( The polymorphism in GSTM1 and GSTT1 genes, leads to complete lack of activity of their corresponding enzymes and is responsible for poor elimination of carcinogenic substances which are potential sources of reactive oxygen species (Rebbeck, 1997

10.1016/j.virusres.2012.11.003 139 SchenkP

EBioMedicine 73 (2021)

Phillips MCL, Murtagh DKJ, Gilbertson LJ, Asztely FJS, Lynch CDP

What happens when they are combined correctly and sequenced specifically is something neither produces alone: a triple-layered repair signal delivered at three tissue levels simultaneously