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Widemann was interviewed by one of her patients, Aidan, who lives with NF1 and was on the selumetinib clinical trial for many years, and she also speaks about the future beyond MEK at the Children's Tumor Foundation 2019 NF Conference
Clinical trials have consistently shown that tirzepatide performs better than expected
Therefore, although this section talks about the effects of lifestyle interventions in diabetes, the same rules apply in prediabetes
If you hit week 16 at 1.7 mg with less than 5% loss and no significant cardiometabolic benefit, a frank conversation with your prescriber about alternative agents (tirzepatide, for example) is appropriate
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