is glp 1 an incretin The Generation and Function of Active GLP-1 GLP-1 receptor agonists are increasingly

Co-treatment of 4d (A2-thio-imidazole derivative), a novel TGR5 agonist, and Sitagliptin (DPP-4 inhibitor) exhibited a GLP-1 secretion and glucose-lowering effect in animal models, while this compound alone exhibits only a slight 1.3-fold increase in GLP-1 secretion [182]

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