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Specifically, SHANK3 plays a pivotal role in regulating glutamatergic synapses, maturation of the dendritic spine, and strengthening the formation and transmission of synapses via glutamate receptors such as AMPARs and NMDARs

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Patients with T2DM reportedly have GSH deficiency when compared to healthy controls [18]

The safety of using GHSs over the short and long term is According to a 2017 review, common side effects of using GHS may include: increased appetite elevated blood sugar levels fluid retention GHSs may also decrease the bodys sensitivity to the hormone insulin, making it more difficult to regulate blood sugar levels

Complement Ther Med (2022) 66:102819