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No dose adjustment is recommended at this time [10]

on the supposed aggravation of COVID-19 ( more topical than ever ( The French Ministry of Health Olivier Veran embracing Micallefs hypothesis, warned the public to avoid NSAIDs like ibuprofen in case of SARS-CoV-2 infection ( On the other hand, the warning was immediately questioned ( Indeed, a closer view to NSAIDs pharmacodynamics might lead to opposite conclusions on their therapeutic value in SARS-CoV-2 infection

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A crucial observation was that DSIPs activating effect on oxidative phosphorylation was selective, primarily increasing V3 without affecting VDNP, and showing no evidence of uncoupling oxidative phosphorylation

[1] Park JR, Lee H, Kim SI, Yang SR