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The calcium-sensing receptor (CaSR) on somatostatin-producing D-cells in the stomach and hypothalamus responds to acute rises in ionized calcium by increasing somatostatin secretion [13]

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This intense inflammation is associated with damaging systemic events like oxidative stress, dysregulation of iron homeostasis, hypercoagulability and thrombus formation, acute respiratory distress syndrome, uncontrolled inflammation and organ failure (251257) (Figure 8)

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