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(31) Discussion The findings from this literature review suggest that GLP-1 receptor agonists influence bone metabolism, wound healing, and surgical outcomes, with both preclinical and clinical evidence supporting potential benefits in orthopedic settings

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gastrointestinal hormones released after nutrient intake with the ability to glucose-dependently augment insulin secretory responses during periods characterized by hyperglycemia) triggered the development of GLP-1 receptor agonists (GLP-1 RAs)