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Importantly, obesity can also worsen pre-existing T2 high asthma, highlighting that its impact is not limited to the obesity-driven asthma endotype but extends across asthma phenotypes [38]

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doi: 10.1007/s10620-024-08729-7 87 FloresABursteinECipherDJFeaginsLA

Anti-inflammatory drugs like glucocorticoids have been shown to limit the pro-inflammatory effects of neutrophils by downregulating key inflammatory factors, including IL-1, TNF-, and IL-8, thus diminishing the neutrophil mediated proinflammatory damage caused by neutrophilic stimuli such as pyocyanin (105, 106)