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doi: 10.1111/acel.13048 164 JohnstonK

The simulation study also explored how, in a physiological environment, the ligands interact with the target as reflected by their hydrogen bonds

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The studies have shown that the reduction in HbA1c was not different between DPP-4 inhibitors and thiazolidinediones, that adverse events, including rate of hypoglycemia, did not differ between the groups and that body weight was increased by thiazolidinedione therapy but not changed by DPP-4 inhibition