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Overall appearance looks more refreshed and youthful, reflecting reduced oxidative stress rather than just cosmetic change

The half-life is similar (approximately one week), but the within-dose bioavailability variation is much higher at 137% per dose

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Fatigue is another underreported side effect

Barriers to taking preventive medication identified in a Canadian study (n = 27 recipients of, and potential candidates for preventive medication) included concern about side effects, aversion to medication, and an aversion to the term chemoprevention (Heisey et al., 2006)