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Post-mortem analyses of TBI patients further reveal increased IDO and kynureninase expression, with higher QA levels associated with poorer six-month outcomes, supporting KP-driven excitotoxicity as a mechanism of secondary brain damage and a potential prognostic marker [254]

Contrary to the conventional renal function biomarkers, CysC exhibits high sensitivity and specificity in monitoring acute and chronic renal impairments

Neuroimaging 6 , 10021012 (2021)