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Oltipraz (4-methyl-5-[2-pyrazinyl]-1,2-dithiole-3-thione) is an Nrf2 inducer that suppresses the benzo[a]pyrene-induced gastric cancer formation, which is not observed in Nrf2 -null mice (Ramos-Gomez et al., 2001)

Gu L, Lu J, Li Q, Wu N, Zhang L, Li H, et al

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10.1016/j.conb.2007.01.002 Curr