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Listen to this article in summarized format Also Read | Dr Reddy's gets nod to roll out generic oral semaglutide drug The sharp decline is fuelled by a rapid expansion in manufacturing, widening supplier base, and expiry of patents in key markets, including India

In addition, GLP-1 can reduce liver cholesterol accumulation by inhibiting SREBP2 and PCSK9, and reduce liver bile acid synthesis by weakening the negative feedback inhibition of bile acid after inhibiting FXR

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At 12 mg over 68 weeks, weight loss reached 28.7%

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