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And the amount of muscle loss during weight loss can dramatically influence metabolism, strength, long-term health, and how sustainable those results actually are

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In the HARMONY-3 clinical trials (104-week randomized, double-blind, placebo- and active-controlled trial assessing the efficacy and safety of albiglutide compared with placebo, sitagliptin, and glimepiride in patients with T2D taking metformin), the efficacy of albiglutide was examined in patients with T2D which was not controlled by metformin alone therapy

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