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Next, to mimic a cellular context, where the antibodies bind the receptor before being released through an endosomal pH-gradient, the antibodies were applied at acidic pH (6.0) to a column coupled with human FcRn followed by elution as a function of a gradual increase in pH toward 8.8 28

96 Experimental studies disc injury type C There are currently no biological studies that investigate complete destructive disc injuries as in fracture dislocations