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In addition, maintaining mental flexibility through undertaking mentally challenging activities regularly, such as learning a new language can be very helpful

The GSH/GPX4 node is the crucial regulator of ferroptosis The GSH system, as a lipid peroxide scavenger, has attracted much attention as a potential therapeutic target for ferroptosis

In fact, it has been suggested that reduced exposure to free radicals and increased intake of antioxidant rich foods or antioxidant supplements will enhance the bodys potential to minimize the risk of free radical related health problems.3 Antioxidants such as polyphenols, ascorbic acid, vitamin A, alpha-lipoic acid, thioredoxin, glutathione, melatonin, coenzyme Q, beta carotenoids, alpha-tocopherols as well as antioxidant enzymes including superoxide dismutase, catalase, glutathione-peroxidases , glutathione reductases and glutathione-s-transferases have been widely investigated for the prevention and treatment of diseases resulting from oxidative damage.4, 5, 6, 7 2

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Carcinogenesis 11 , 21792183 (1990)