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Use in Specific Populations The safety in children, pregnant women, breastfeeding mothers, or immunocompromised patients is unknown

Additionally, the roles of ROS and mitophagy in RA are complex and diverse, with ROS inducing mitochondrial autophagic behavior and enhancing mitochondrial autophagic activity, possibly contributing to the survival of FLSs and increasing the inflammatory response, and inhibition of autophagy inducing apoptosis of FLSs (303)

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