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Each component engages separate but convergent molecular targets involved in hypothalamic and pituitary regulatory systems, making the blend of interest for experimental models examining coordinated endocrine signaling

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Bock-Marquette I, Saxena A, White MD, Dimaio JM, Srivastava D

Significant weight loss particularly reduction of visceral fat is associated with improvements in testosterone levels in men with obesity-related hypogonadism, as visceral fat drives conversion of testosterone to oestrogen

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