Oxidative stress is the most important of these, occurring when ROS overwhelm cellular antioxidant capacity
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Nature provides options and saffron, especially the clinically tested Affron extract, is one of the most promising
For example, studies using radiolabeled exenatide have shown that it can readily enter the mouse brain, though this central uptake appears to diminish at higher doses (Kastin and Akerstrom, 2003)
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