glp-1 eye issues Study: Ozempic linked to condition that can cause vision loss Frontiers | Unlocking the potential

When intra-portal insulin levels are increased (e.g., obesity, Cushings syndrome, or due to treatment with glucocorticoids and glucagon-like peptide 1 receptor agonists) or decreased (e.g., malnutrition, anorexia nervosa and type 1 diabetes mellitus), these changes secondarily alter hepatic GH sensitivity resulting in a secondary association with discordant GH and IGF-I levels (e.g., high GH/low IGF-I levels or low GH/high IGF-I levels, respectively)

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Triggering of eryptosis, the suicidal erythrocyte death by mammalian target of rapamycin (mTOR) inhibitor temsirolimus

Rhee SH, Pothoulakis C, Mayer EA (2009) Principles and clinical implications of the brain-gut-enteric microbiota axis