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(C) Mitochondrial GSH level assayed by HA-MITO tag immunoisolation followed by MS-based metabolite profiling in the control and clonal A39 CRIPSR KO K562 cells expressing the indicated A39 constructs

Estimula la produccin de colgeno de tipos I, III y IV, elastina, proteoglicanos y glicosaminoglicanos en la dermis

10.1016/j.fct.2020.111588 75 MartnM.MacasM.EscamesG.LenJ.Acua-CastroviejoD

Glutamine metabolism regulates ferroptosis: glutaminase 2 (GLS2) is a novel p53 target, and p53 promotes ferroptosis by activating GLS2 (142)

therefore, they connect the activity of antioxidants in the membranes and in the cytoplasm, increasing the antioxidant network inside the cells