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Agnieszka Sirko (Institute of Biochemistry and Biophysics, Warsaw, Polish Academy of Sciences)

On the one hand, high levels of cholesterol are linked to atherosclerosis 1 , NAFLD/NASH 2 , obesity/diabetes 3 and cancer 4

Firstly, the length of the study was likely not long-enough to measure true long-term weight loss maintenance, and both groups may have simply continued with the dietary changes they had made during the 9-week weight loss period

The side effects of supplements arise from their specific ingredients

Glycemic efficacy, weight effects, and safety of once-weekly glucagon-like peptide-1 receptor agonists