retatrutide approved in other countries (LY3437943) | GCGR/GIPR/GLP-1R Agonist Eli Lilly Preparing Retatrutide Applications

Glycemic control: In type 2 diabetes patients, HbA1c dropped by 1.32.0% (from ~8.0% to ~6.0%) with 412 mg doses [1]

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Effects of various antidepressants on serum thyroid hormone levels in patients with major depressive disorder

Lightheadedness, flushing, brief headache or nausea

NICE guidance (NG28) recommends considering dose reductions of insulin or sulfonylureas when initiating a GLP-1 receptor agonist to mitigate this risk