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Understanding these effects helps clinicians provide targeted advice about dietary modifications and symptom management strategies that may mitigate gastrointestinal disturbance whilst maintaining therapeutic efficacy

In the meantime, the broader field of IN drug delivery has witnessed exponential growth with frequent publications about other novel IN formulations and delivery technologies for CNS-targeted therapies

Exercise avoidance behaviour is a sensitive indicator of substance-induced malaise in mice 35

Studies on peptide stability show that pH shifts during lyophilization can affect degradation rates in reconstituted solutions [5]

Similar to blood-brain barrier but some structural differences