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This notion is supported by the following results: (i) The maintenance of the Grx1roGFP2 redox state in the IMS is dependent on the presence of porins (Por1) in the OMM (Figure 6)

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[3] GSTs are essential in this process because they catalyze the nucleophilic attack of glutathione on various electrophilic residues of xenobiotic substrates, thereby preventing their disruption of vital cellular proteins and nucleic acids

Holmstrom, K