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Clinicians will map your weight trajectory, the timing of perimenopausal symptoms, and whether rapid fat loss could shift estrogen availability, all of which change how you tolerate and respond to both HRT and GLP-1 treatments

Weigh the risks of side effects Despite reports of some serious side effects, Levy says these medications have a pretty solid safety record

The earlier you detect these symptoms, the more effectively you can manage them

Your results may vary based on: Your starting weight Your dosage Individual response to the medication Diet and physical activity Other medications you may be taking "Healthy habits, like quality exercise and sleep, can also help offset the adverse side effects often accompanying these medications, such as gut issues and loss of lean body mass

Once used, the pen should be discarded after the injection, since Wegovy pens are intended for single use