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Tirzepatide is FDA-approved for type 2 diabetes (as Mounjaro) and for obesity (as Zepbound)
25 A more recent Cochrane review of the pharmacologic treatment of low back pain (also not specific to lumbar spinal stenosis) found that NSAIDs, muscle relaxants, and opioids had a small effect on pain reduction, but use of muscle relaxants and opioids was complicated by a significant risk of adverse effects
No pharmaceutical company, no academic medical center, and no government agency has found the existing preclinical data compelling enough to fund a rigorous human trial in over 30 years
While semaglutide does not require dose adjustment for mild to moderate renal impairment, experience in patients with severe renal impairment is limited
Proper IM Injection Sites Choosing the right spot for the shot is key
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