Ferulic acid alleviates alveolar epithelial barrier dysfunction in sepsis-induced acute lung injury by activating the Nrf2/HO-1 pathway and inhibiting ferroptosis
Oxidative stress results in increased expression of calreticulin, Psme3, and vimentin, which regulate TGF-1-induced proliferation and epithelial-mesenchymal transition (EMT) by modulating Smad signaling 33,34
in other words, podocyte IR gives rise to the albuminuric feature
*Correspondence: Lili Zhou, [email protected] These authors have contributed equally to this work This article was submitted to Renal Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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