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Most procedures require one to three weeks off work, depending on the extent of surgery and your jobs physical demands

The slope is clearly upward and sustained

This starting dose provides minimal therapeutic effect but allows the body to adjust to the medication

This is especially problematic with injectable medications given the extra work associated with an injection, as well as the potential aversion to self-injecting medication

Importantly, the ECD of GLP-1R undergoes a remarkable orientation change from the closed TMD-interacting conformation to the extended active conformation during peptide binding and activation