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The mechanism probably involve an effect of FLNA in regulating lysosomal degradation of SSTR2, since SST2 ligand-induced down-regulation was abolished when lysosomal degradation was prevented

The role of common variants of ABCB1, CYP3A4, and CYP3A5 genes in lipid-lowering efficacy and safety of simvastatin treatment

doi: 10.3389/fcell.2021.630503 Received 17 November 2020 Accepted 11 February 2021 Published 18 March 2021 Volume 9 - 2021 Edited by Isabel R

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