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Cell 148:399408

For full prescribing information, please refer to the Summary of Product Characteristics on medicines.org.uk

Gastroparesis Exacerbation by a GLP-1 Agonist. Journal of the Endocrine Society, vol

Combining these therapies is based on their complementary mechanisms, though large-scale clinical trials on this specific combination are limited

In consideration of the multiple metabolic and cardiovascular effects seen in subjects treated with GLP-1RAs and SGLT-2is (e.g., reduction of hyperglycemia, weight loss, free/fat mass and bone remodeling, anti-atherosclerosis, natriuresis), it is reasonable to speculate that GH and IGF-1 may play a about a relevant role in this context