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Rapid Method to Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1-Transfected Human Embryonic Kidney 293 Cells

The safe switching protocol Write down your current dose in milligrams (not units) Identify your new vial concentration (check the label, not memory) Use the formula: Units = (mg dose / new concentration) x 100 Verify by working backward: (new units / 100) x new concentration = original mg dose Have someone else check your math if possible This protocol takes two minutes

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