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As their use has expanded beyond their initial indications, GLP-1 receptor agonists are poised to have more far-reaching societal impacts, influencing aspects of public health, healthcare economics, as well as even social perceptions of obesity and weight management

In the perioperative management of patients taking SGLT2 inhibitors, the optimal approach for preventing EDKA is to withhold the medication in any setting where predisposing factors for ketoacidosis are present (e.g

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Advanced techniques like fluorescence in situ hybridization can detect the deletion in the 15q11-q13 parts of the gene, and chromosomal microarray can detect if both copies of the gene are from the mother

Further research is warranted to determine whether GLP-1 RAs are being prescribed primarily for metabolic indications in this group or whether clinical use is expanding to include PCOS-related symptoms and outcomes