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For patients whose primary goal is weight loss, MOTS-c works best paired with diet, training, and sometimes a GLP-1 medication or another peptide rather than as a standalone weight-loss tool

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In an animal model, semaglutide demonstrated neuroprotective effects and improved cognitive function by inhibiting the release of inflammatory cytokines mediated by the NLRP3 inflammasome, a protein involved in regulating the innate immune system and inflammatory responses

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