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doi:10.1210/clinem/dgaa327 59

[DOI] [PMC free article] [PubMed] [Google Scholar] 94.Pu S., Ren L., Liu Q

Looks like reta placed you in a normal HR range now, lol

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Selective biodistribution in inflamed tissues due to enhanced permeability and the resultant lower effective dose and longer duration of drug action leading to decreased dose frequency are a recurring theme with nano-medicines in RA models with less systemic side-effects [28]