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The concentration of GSH that is normally about 400 M in the epithelial lining fluid, over a 100-fold higher than in plasma, is low in the airways of patients with cystic fibrosis from an early age (112114)

This can happen for several reasons, from trauma and infections to inherited conditions

This success led to the development of exenatide, the first GLP-1 receptor agonist approved by the FDA for the treatment of diabetes (in 2004)

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The health department also receives a very small budget from the government and hence, the majority of patients still rely on cheap and easily available treatments, such as interferon and peginterferon