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For example, the metabolism of nitroglycerin requires interaction with thiols such as cysteine and GSH for transformation to vasoactive metabolites such as nitrosothiols or nitric oxide

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While these remain the cornerstone of treatment, a growing body of evidence suggests that medications can offer significant help particularly for people struggling to make enough lifestyle changes to reverse the process alone

However, a presenter here said the addition of strength training may mitigate these adverse outcomes