does semaglutide affect the gallbladder Ozempic After Removal: Safety & Guidelines GLP-1 Without a Gallbladder |

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Mechanism of action Ozempic (semaglutide) works on the GLP-1 receptors, whereas Zepbound (tirzepatide) is a dual receptor agonist that binds to glucagon-like-peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) receptors in the body

GLP-1 intolerance or non-candidacy: Patient has tried GLP-1 therapy and could not tolerate it, or is not a clinical candidate