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Patients with histamine issues can also face problems if they start taking BPC 157 right away

Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG)

8 Where results are unclear, serum MMA and homocysteine levels (both of which accumulate with B12 deficiency as discussed above) can also be used to confirm a diagnosis, although homocysteine is not specific to B12 deficiency, as it may also be caused by deficiencies in other B vitamins

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It follows the same regulatory arc as BPC-157 and TB-500: Category 2 placement in 2023, removal from Category 2 in April 2026, and formal PCAC review scheduled for July 23, 2026