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3-4

Storage Timeline Lyophilized Solids: Stable at room temperature for up to 4 weeks during transit, but must be transferred to long-term storage at -20C upon receipt

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Abbreviations DPP-4: Dipeptidyl peptidase-4 EMA: European Medicines Agency EPAC: Exchange protein directly activated by cAMP FDA: Food and Drug Administration FGF21: Fibroblast growth factor 21 GIP: Glucose-dependent insulinotropic polypeptide GLP-1: Glucagon-like peptide-1 PKA: Protein kinase A SGLT-2: Sodiumglucose cotransporter 2 References Moore B, Edie ES, Abram JS (1906) On the treatment of diabetes mellitus by acid extract of duodenal mucous membrane

Add the diluent slowly down the inside wall of the vial rather than directly onto the lyophilized powder, and let it dissolve without vigorous shaking