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Side Effects Profile All three medications share common side effects, primarily gastrointestinal: Nausea (usually temporary, worst in first few weeks) Diarrhea or constipation Abdominal discomfort Reduced appetite (this is the goal, but can feel uncomfortable initially) The higher dose of Wegovy may cause more pronounced side effects initially, while Saxendas daily dosing can offer more stable blood levels with potentially fewer ups and downs

Although several drugs are under investigation, there are currently no approved drugs for NAFLD ( The pathogenetic role of oxidative stress in NALFD is well known and would explain the rationale for the use of GSH as a potential therapy

Figure 6.11 Hydrolysis of procainamide to p-aminobenzoic acid by amidase

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