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The disadvantage is that higher doses require large injection volumes

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(4) CMS determines the time period during which an ACO is affected by a cyberattack, including ransomware/malware, as follows: (i) CMS uses the start and end date indicated on an ACO's application to the Quality Payment Program for an extreme and uncontrollable circumstance exception due to a cyberattack, including ransomware/malware, or the start date indicated on the application and an end date subsequently provided by the ACO in the form and manner as specified by CMS