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These results are not surprising for a drug developed for the treatment of T2D
doi: 10.1016/0140-6736(92)92814-v 24 BugianesiEMoscatielloSCiaravellaMFMarchesiniG
Schwartz for their contribution to the peer review of this work
Co-agonism showed, on murine models, the capability to improve insulin secretion and sensitivity in a weight-dependent and weight-independent manner, probably through its action on nutrient metabolism (49, 50), preventing their accumulation and thus making these organs actively involved in metabolism with an improvement in insulin sensitivity and WL, yielding long-lasting effects
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