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New York: Saunders Elsevier

Primary and secondary endpoints Primary endpoints of the present study were changes in % FMD, IMT, PAI-1, VCAM-1, MCP-1, BNP, hs-CRP, IL-6, TNF-, endothelin, E-selectin and resistin while the secondary endpoints were the changes in serum levels of adiponectin, leptin, total cholesterol, HDL-cholesterol, LDL-cholesterol and triglyceride

43, 44 Urotensin-II has also been shown to function as a potent vasodilator in some isolated vessels

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By activating multiple pathways involved in appetite regulation, insulin sensitivity and energy expenditure, It produces stronger metabolic effects than earlier generations of weight loss medications