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and (3) the latest epidemiological evidence from case-control and cohort studies evaluating BC risk in female night shift workers, while considering the heterogeneity caused by exposure misclassification and other confounding factors

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133 Importantly, S6K1 depletion, which is a component of mTOR signaling, also leads to a prolonged lifespan in mice

Valine-Citrulline (VCit) is a prominent enzymatic unit in approved ADCs, designed for selective hydrolysis by lysosomal proteases at the amide bond between citrulline and the p-aminobenzyl carbamate (PABC) spacer (Figure 5)